Interpret the research
Brief, practical analysis of the advances shaping human cell models, with attention to what a technology enables and where its limitations remain.

Human Cell Model Exchange (HCMX) is an independent, scientist-led publication and community for new approach methodologies (NAMs), organoids, assembloids, induced pluripotent stem cells (iPSCs) and stem cell research.
We connect the evidence, methods and people advancing human-relevant biology—from reproducible differentiation protocols to the technologies moving complex cell models into discovery and translation.
HCMX covers human iPSC models, adult and pluripotent stem cells, organoids, assembloids, co-cultures, organ-on-chip systems and other NAMs that can improve mechanistic research, disease modelling, safety assessment and therapeutic development.
Brief, practical analysis of the advances shaping human cell models, with attention to what a technology enables and where its limitations remain.
Structured protocols preserve materials, catalogue numbers, concentrations, preparation, validation and community context so experiments are easier to assess and reproduce.
Researchers can contribute protocols and articles, discuss published records, rate their usefulness and find opportunities across academia and biotechnology.
We distinguish source evidence from HCMX interpretation, flag unresolved details and avoid turning a promising model into a stronger claim than the data support.
Our goal is a clear, searchable record of how human-relevant models are built, validated and applied—one that improves as the community adds experience.
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